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L-Theanine-d5

L-Theanine-d5 is the deuterium labeled L-Theanine. L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. L-Theanine causes anti-stress effects via the inhibition of cortical neuron excitation by oral intake[1][2][3].

Product Specifications

CAS Number

1217451-85-8

Product Name Alternative

L-Glutamic Acid γ-ethyl amide-d5; Nγ-Ethyl-L-glutamine-d5

UNSPSC

12352211

Target

Apoptosis; Endogenous Metabolite

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Purity

99.9

Solubility

H2O : 150 mg/mL (ultrasonic; warming)

Smiles

OC([C@@H](N)CCC(NC([2H])([2H])C([2H])([2H])[2H])=O)=O

Molecular Formula

C7H9D5N2O3

Molecular Weight

179.23

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Vuong QV, et al. L-Theanine: properties, synthesis and isolation from tea. J Sci Food Agric. 2011 Aug 30;91 (11) :1931-9.|[3]Kimura K, et al. L-Theanine reduces psychological and physiological stress responses. Biol Psychol. 2007 Jan;74 (1) :39-45.|[4]Takeshima M, et al. l-Theanine protects against excess dopamine-induced neurotoxicity in the presence of astrocytes. J Clin Biochem Nutr. 2016 Sep;59 (2) :93-99.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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