Vafidemstat
Vafidemstat (ORY-2001) is an oral, brain penetrant, dual lysine-specific histone demethylase (LSD1) /MAO-B inhibitor[1].
Product Specifications
CAS Number
[1357362-02-7]
Product Name Alternative
ORY-2001
UNSPSC
12352005
Target
Histone Demethylase; Monoamine Oxidase
Type
Reference compound
Related Pathways
Epigenetics; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Vafidemstat.html
Purity
98.03
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
NC1=NN=C(O1)CN[C@H]2[C@H](C3=CC=C(OCC4=CC=CC=C4)C=C3)C2
Molecular Formula
C19H20N4O2
Molecular Weight
336.39
References & Citations
[1]ORYZON presents data on the Phase I trial with ORY-2001 at the 13th International Conference on Alzheimer’s and Parkinson’s diseases|[2]ORYZON Reports Financial Results and Corporate Update for the 1st Half Ended June 30, 2018.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
KDM1/LSD1
Available Sizes
Curated Selection
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