Mal-PEG4-propargyl
Mal-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Mal-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[1262681-30-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-peg4-propargyl.html
Purity
99.68
Solubility
10 mM in DMSO
Smiles
O=C(C=C1)N(CCOCCOCCOCCOCC#C)C1=O
Molecular Formula
C15H21NO6
Molecular Weight
311.33
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6008122-02 5x 0.2 mL
CLEC9A, ID (CLEC9A, C-type lectin domain family 9 member A)
Ask
View Details 
BRE1201 120 Cases / 120 Cores
Breast cancer tissue array (most of triple negative), including pathology grade, TNM, clinical stage and IHC markers (ER, PR, Her-2), 120 cases/120 cores
Ask
View Details