(Rac) -Finerenone
(Rac) -Finerenone ((Rac) -BAY 94-8862) is the racemate of Finerenone. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM) . Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold) [1].
Product Specifications
CAS Number
[1050477-27-4]
Product Name Alternative
(Rac) -BAY 94-8862
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Mineralocorticoid Receptor
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/rac-finerenone.html
Concentration
10mM
Purity
99.66
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
N#CC(C=C1OC)=CC=C1C2C3=C(C(C)=CN=C3OCC)NC(C)=C2C(N)=O
Molecular Formula
C21H22N4O3
Molecular Weight
378.42
Precautions
P264-P280-P302+P352-P362+P364
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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