Uridine

Uridine (β-Uridine) is a nucleoside compound composed of uracil and a ribose ring, which are connected by a β-N1-glycosidic bond[1].

Product Specifications

CAS Number

[58-96-8]

Product Name Alternative

β-Uridine

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; NF-κB; Nucleoside Antimetabolite/Analog

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Uridin.html

Purity

99.98

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

O[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1CO

Molecular Formula

C9H12N2O6

Molecular Weight

244.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Sokoloski JA, et al., Effects of uridine on the growth and differentiation of HL-60 leukemia cells. Leuk Res. 1991;15 (11) :1051-8. |[2]Zheng WV, et al., Uridine alleviates carbon tetrachloride-induced liver fibrosis by regulating the activity of liver-related cells. J Cell Mol Med. 2022 Feb;26 (3) :840-854. |[3]Krylova IB, et al., Uridine treatment prevents myocardial injury in rat models of acute ischemia and ischemia/reperfusion by activating the mitochondrial ATP-dependent potassium channel. Sci Rep. 2021 Aug 20;11 (1) :16999.