CARM1-IN-6
CARM1-IN-6 (Compound iCARM1) is an effective and selective inhibitor of CARM1 with an IC50 value of 12.3 μM. CARM1-IN-6 exhibits cell growth inhibitory activity and can be used in cancer research[1].
Product Specifications
CAS Number
1269199-96-3
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/carm1-in-6.html
Concentration
10mM
Purity
99.5900
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN(C)CCN(CC1)CCN1C2=NC=C(C(C3=CC=C(C)C=C3)=N2)C4=COC=C4
Molecular Formula
C23H29N5O
Molecular Weight
391.51
References & Citations
[1]Peng BL, et al. A CARM1 Inhibitor Potently Suppresses Breast Cancer Both In Vitro and In Vivo. J Med Chem. 2024 May 23;67 (10) :7921-7934.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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