5-Phenylpentan-2-one
5-Phenylpentan-2-one is a potent histone deacetylases (HDACs) inhibitor. 5-Phenylpentan-2-one can be used for urea cycle disorder research[1][2].
Product Specifications
CAS Number
2235-83-8
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/5-phenylpentan-2-one.html
Concentration
10mM
Purity
99.81
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC(CCCC1=CC=CC=C1)=O
Molecular Formula
C11H14O
Molecular Weight
162.23
Precautions
H315, H319, H335
References & Citations
[1]Sabrina Paganoni, et al. Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis. N Engl J Med. 2020 Sep 3;383 (10) :919-930.|[2]Sabbir Khan, et al. Phenylbutyrate and β-cell function: contribution of histone deacetylases and ER stress inhibition.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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