5-Phenylpentan-2-one

5-Phenylpentan-2-one is a potent histone deacetylases (HDACs) inhibitor. 5-Phenylpentan-2-one can be used for urea cycle disorder research[1][2].

Product Specifications

CAS Number

[2235-83-8]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/5-phenylpentan-2-one.html

Concentration

10mM

Purity

99.81

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC(CCCC1=CC=CC=C1)=O

Molecular Formula

C11H14O

Molecular Weight

162.23

Precautions

H315, H319, H335

References & Citations

[1]Sabrina Paganoni, et al. Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis. N Engl J Med. 2020 Sep 3;383 (10) :919-930.|[2]Sabbir Khan, et al. Phenylbutyrate and β-cell function: contribution of histone deacetylases and ER stress inhibition.