SARS-CoV-2-IN-97

SARS-CoV-2-IN-97 (Compound CO-01) is an inhibitor for SARS-CoV-2 Nsp15 endoribonuclease with an IC50 of 53.5 μM. SARS-CoV-2-IN-97 exhibits low cytotoxicity in A549-AT cell with IC50 of 134 μM[1].

Product Specifications

CAS Number

[364338-71-6]

UNSPSC

12352101

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sars-cov-2-in-97.html

Smiles

BrC1=CC(Br)=CC2=C1NC(/C2=C(C#N)\C#N)=O

Molecular Formula

C11H3Br2N3O

Molecular Weight

352.97

References & Citations

[1]Rampias T, et al. Exploration of isatin-based inhibitors of SARS-CoV-2 Nsp15 endoribonuclease[J]. European Journal of Medicinal Chemistry, 2024: 116886.