Auristatin23
Auristatin23, a conjugate of Auristatin F (HY-15583), is a cytotoxin. Auristatin23 exhibit cytotoxic activities towards targeted cells, including abnormal cells such as cancer cells, that are MDR+ [1].
Product Specifications
CAS Number
[2375388-36-4]
UNSPSC
12352005
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/auristatin23.html
Solubility
10 mM in DMSO
Smiles
OC([C@H](CC1=CC=CC=C1)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)CCCCN(C)C(OC(C)(C)C)=O)=O)=O)=O)OC)=O)=O
Molecular Formula
C49H84N6O10
Molecular Weight
917.23
References & Citations
[1]Doronina SO, et. Hydrophobic auristatin f compounds and conjugates thereof. WO2019164987A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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