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MicroRNA-21-IN-3

MicroRNA-21-IN-3 (compound 45) can specifically bind to the precursor of oncogenic and pro-inflammatory microRNA-21 with medium nanomolar affinity, reduce cancer cell proliferation and miR-21 levels, and can be used in antitumor research[1].

Product Specifications

CAS Number

[2766106-83-4]

UNSPSC

12352005

Hazard Statement

H302-H314

Target

MicroRNA

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/microrna-21-in-3.html

Purity

98.0

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

O=C1N=C(NC2=C1C=CN=C2)NC3=NC=C(N4CCNCC4)C=C3

Molecular Formula

C16H17N7O

Molecular Weight

323.35

Precautions

P260-P264-P270-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P330-P363-P405-P501

References & Citations

[1]Matthew D Shortridge, et al. Drug-Like Small Molecules That Inhibit Expression of the Oncogenic MicroRNA-21. ACS Chem Biol. 2023 Feb 17;18 (2) :237-250.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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