Relebactam
Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases and KPC) and class C (AmpC) enzymes. Relebactam shows antibacterial activity[1].
Product Specifications
CAS Number
1174018-99-5
Product Name Alternative
MK-7655
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Bacterial; Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Relebactam.html
Purity
99.86
Solubility
DMSO : 175 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
Smiles
O=S(ON1[C@]2([H])CC[C@@H](C(NC3CCNCC3)=O)[N@@](C2)C1=O)(O)=O
Molecular Formula
C12H20N4O6S
Molecular Weight
348.38
Precautions
H315, H319, H320
References & Citations
[1]Lapuebla A, et al. Activity of Imipenem with Relebactam against Gram-Negative Pathogens from New York City. Antimicrob Agents Chemother. 2015 Aug;59 (8) :5029-31.|[2]Bush K. A resurgence of β-lactamase inhibitor combinations effective against multidrug-resistant Gram-negative pathogens. Int J Antimicrob Agents. 2015 Nov;46 (5) :483-93.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
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