TRFS-green
TRFS-green is a highly selective off−on fluorescent probe for imaging selenoprotein thioredoxin reductase (TrxR) in living cells. TRFS-green has the maximum absorbance at around 373 nm. After it is activated by TrxR, the maximum absorbance shifts to around 440 nm[1].
Product Specifications
CAS Number
1513848-14-0
UNSPSC
12352005
Target
TrxR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/trfs-green.html
Concentration
10mM
Purity
97.0
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(OC1CSSC1)NC2=CC=C(C3=C4C=CC=C32)C(N(CCCC)C4=O)=O
Molecular Formula
C20H20N2O4S2
Molecular Weight
416.51
References & Citations
[1]Liangwei Zhang, et al. Highly selective off-on fluorescent probe for imaging thioredoxin reductase in living cells. J Am Chem Soc. 2014 Jan 8;136 (1) :226-33.|[2]Xinming Li, et al. A fast and specific fluorescent probe for thioredoxin reductase that works via disulphide bond cleavage. Nat Commun. 2019 Jun 21;10 (1) :2745.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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