Chromafenozide

Chromafenozide is a potent partial ecdysone receptor agonist and dibenzoylhydrazine insecticide. Chromafenozide inhibits insect feeding and causes the insect to molt prematurely, leading to death. Chromafenozide shows antagonistic activity against 20-HE. Chromafenozide shows high toxicity against Spodoptera exigua and Spodoptera littoralis[1][2][3][4][5].

Product Specifications

CAS Number

[143807-66-3]

Product Name Alternative

ANS118

UNSPSC

12352005

Hazard Statement

H411

Target

Insecticide

Type

Reference compound

Related Pathways

Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Chromafenozide.html

Purity

99.65

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C2C(CCCO2)=C1C)NN(C(C3=CC(C)=CC(C)=C3)=O)C(C)(C)C

Molecular Formula

C24H30N2O3

Molecular Weight

394.51

Precautions

H411

References & Citations

[1]Toya T, et al. Potent and selective partial ecdysone agonist activity of chromafenozide in Sf9 cells. Biochem Biophys Res Commun. 2002 Apr 12;292 (4) :1087-91.|[2]Mosallanejad H, et al. Non-steroidal ecdysteroid agonist chromafenozide: Gene induction activity, cell proliferation inhibition and larvicidal activity. Pesticide Biochemistry and Physiology, 2008, 92 (2) : 70-76.|[3]Morou E, et al. A new dibenzoylhydrazine with insecticidal activity against Anopheles mosquito larvae. Pest Manag Sci. 2013 Jul;69 (7) :827-33.|[4]Sardar SW, et al. Residual characteristics and safety assessment of the insecticides spiromesifen and chromafenozide in lettuce and perilla. Sci Rep. 2022 Mar 18;12 (1) :4675.|[5]Zhao M A, et al. Human exposure and risk assessment of chromafenozide during treatment in rice fields. Human and Ecological Risk Assessment: An International Journal, 2016, 22 (1) : 116-125.