ATP (disodium salt hydrate)
ATP disodium salt hydrate (Adenosine 5'-triphosphatedisodium salt hydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation[1][2].
Product Specifications
CAS Number
[34369-07-8]
Product Name Alternative
Adenosine 5'-triphosphate (disodium salt hydrate)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/atp-disodium-salt-hydrate.html
Purity
99.64
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
OP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C3=NC=NC(N)=C3N=C2)O1)(OP(OP(O)(O[Na])=O)(O[Na])=O)=O.[H]O[H].[x]
Molecular Formula
C10H14N5O13Na2P3.xH2O
Precautions
H302, H315, H319, H335
References & Citations
[1]Bonora M, et al. ATP synthesis and storage. Purinergic Signal. 2012 Sep;8 (3) :343-57.|[2]M J L Bours, et al. Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther. 2006 Nov;112 (2) :358-404.|[3]Shuo Xu, et al. Doxycycline inhibits NAcht Leucine-rich repeat Protein 3 inflammasome activation and interleukin-1β production induced by Porphyromonas gingivalis-lipopolysaccharide and adenosine triphosphate in human gingival fibroblasts. Arch Oral Biol. 2019 Nov;107:104514.|[4]Yang Xiang, et al. Adenosine-5'-Triphosphate (ATP) Protects Mice against Bacterial Infection by Activation of the NLRP3 Inflammasome. PLoS One. 2013; 8 (5) : e63759.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite
Citation 01
Int Immunopharmacol. 2023 Apr:117:109917.|Phytomedicine. 2025 Oct 25:148:157454.|. 2022 Nov 4.|ACS Nano. 2023 Dec 12;17 (23) :23872-23888.|Acta Pharmacol Sin. 2022 Aug;43 (8) :2016-2025.|Acta Pharmacol Sin. 2025 Apr 7.|Acta Pharmacol Sin. 2025 Jul 17.|Adv Sci (Weinh) . 2025 Jun 10:e01532.|Adv Sci (Weinh) . 2025 Nov 11:e08957.|Adv Sci (Weinh) . 2025 Sep 26:e08991.|Aging (Albany NY) . 2021 Mar 10;13 (6) :8588-8598.|Aging (Albany NY) . 2021 Sep 28;13 (18) :22588-22610.|Am J Chin Med. 2025;53 (2) :501-522.|Anal Chem. 2025 May 13;97 (18) :9827-9835.|Anal Chim Acta. 2021 Dec 15:1188:339180.|Antioxidants (Basel) . 2022 Nov 23;11 (12) :2315.|Antioxidants (Basel) . 2023 Jun 19;12 (6) :1304.|Appl Microbiol Biotechnol. 2024 Jan 25;108 (1) :173.|Arch Oral Biol. 2019 Nov:107:104514.|Autophagy. 2025 Apr 4:1-18.|Autophagy. 2025 Aug 16.|Biochem Biophys Res Commun. 2024 May 14:708:149814.|Biochem Pharmacol. 2024 Jun 19:116377.|Biochem Pharmacol. 2025 Feb 12:234:116801.|Biochemistry. 2023 Dec 5;62 (23) :3396-3410.|Biochim Biophys Acta Mol Basis Dis. 2024 Jan;1870 (1) :166895.|Biochim Biophys Acta Mol Cell Res. 2024 Jan;1871 (1) :119595.|Biochim Biophys Acta Mol Cell Res. 2024 Mar 22;1871 (4) :119712.|Biomed Pharmacother. 2024 Jul 15:177:117111.|Biomed Pharmacother. 2024 Jun 21:177:117006.|Biomed Pharmacother. 2024 Jun 24:177:116952.|Biomed Pharmacother. 2025 Jun 17:189:118275.|Biomed Pharmacother. 2025 Nov 12:193:118748.|Bioorg Med Chem. 2021 Jan 1;29:115899.|bioRxiv. 2024 Apr 21.|Biosens Bioelectron. 2021 Apr 15;178:113025.|Br J Pharmacol. 2025 May 13.|Brain Mechanisms. 2025 Nov 21.|Cancer Cell Int. 2023 May 9;23 (1) :87.|Cancer Lett. 2024 Jul 29:217145.|Cancer Res. 2025 Jul 25.|Carbohyd Polym. 2020 Jun 1;237:116163.|Cardiovasc Pathol. 2025 Jul 4:79:107750.|Cell Commun Signal. 2025 Jul 8;23 (1) :327.|Cell Death Differ. 2022 Feb;29 (2) :439-450.|Cell Death Differ. 2025 Nov 10.|Cell Death Dis. 2021 Dec 14;12 (12) :1159.|Cell Death Dis. 2022 Oct 8;13 (10) :860.|Cell Death Dis. 2020 Feb 18;11 (2) :132. |Cell Prolif. 2023 Sep;56 (9) :e13442.|Cell Rep. 2021 Aug 10;36 (6) :109516.|Cell Rep. 2024 Jun 27;43 (7) :114402.|Cell Rep. 2025 Jan 10;44 (1) :115203.|Cell Rep. 2025 Nov 25;44 (12) :116620.|Cell Res. 2025 Feb;35 (2) :97-116.|Cell. 2025 Jul 10;188 (14) :3744-3756.e16.|Cell. 2025 Jul 24;188 (15) :4025-4042.e20.|Clin Oral Investig. 2023 Jun;27 (6) :2875-2885.|Crit Care. 2021 Oct 12;25 (1) :356.|Cytotechnology. 2025 Apr;77 (2) :66.|EMBO J. 2025 Aug 18.|Eur J Pharmacol. 2022 Feb 5:916:174729.|Eur J Pharmacol. 2023 May 15:947:175681.|Exp Neurol. 2026 Feb:396:115537.|Food Funct. 2025 Jun 16;16 (12) :4731-4753.|Front Neurosci. 2022 Jun 7;16:901688.|Heliyon. 2024 Sep 19;10 (19) :e38050.|Immunity. 2024 Mar 12;57 (3) :495-512.e11.|Immunity. 2025 Aug 12:S1074-7613 (25) 00314-0.|Immunotargets Ther. 2024 Dec 14:13:775-788.|Int Immunopharmacol. 2023 Mar:116:109747.|Int Immunopharmacol. 2024 Nov 2;143 (Pt 3) :113527.|Int Immunopharmacol. 2025 Jan 18:148:114057.|Int Immunopharmacol. 2025 Oct 22:167:115697.|Int Immunopharmacol. 2025 Sep 5:165:115437.|Int J Biochem Cell Biol. 2026 Jan:190:106880.|Int J Biol Macromol. 2024 Apr 27;268 (Pt 2) :131779.|Int J Dev Neurosci. 2023 Feb;83 (1) :53-66.|Int J Mol Sci. 2024 Sep 26;25 (19) :10366.|J Agric Food Chem. 2024 Sep 25;72 (38) :20959-20973.|J Cell Mol Med. 2025 Jan;29 (2) :e70338.|J Dent Sci. 2025 Jul;20 (3) :1422-1435.|J Ethnopharmacol. 2024 Feb 10:320:117388.|J Ethnopharmacol. 2024 Jun 28:328:118057.|J Ethnopharmacol. 2025 Jul 30;353 (Pt A) :120346.|J Inflamm Res. 2025 Jul 19:18:9587-9608.|J Transl Med. 2024 Sep 27;22 (1) :871.|J Virol. 2023 Mar 30;97 (3) :e0000323.|Life Sci. 2021 Apr 15:271:119192.|Mater Today Bio. 2025 Feb 1:31:101539.|Mater Today Bio. 2025 May 10:32:101838.|Mol Cell. 2022 Jun 2;82 (11) :2032-2049.e7.|Mol Cell. 2023 Jun 15;83 (12) :2137-2147.e4.|Mol Immunol. 2024 May:169:86-98.|Mol Med. 2025 Jun 16;31 (1) :240.|Neurochem Int. 2025 Jul:187:105992.|Nutrients. 2021 Dec 14;13 (12) :4462.|Oral Dis. 2021 Jul;27 (5) :1148-1160.|Phytomedicine. 2024 Jan:123:155193.|Phytomedicine. 2025 Dec:149:157563.|Phytomedicine. 2025 Jul:142:156698.|Phytomedicine.2023 Sep:118:154971.|Placenta. 2025 May 22:167:204-215.|Proc Natl Acad Sci U S A. 2025 Feb 25;122 (8) :e2424906122.|Protein Cell. 2022 Apr;13 (4) :281-301.|Reprod Biomed Online. 2024 Oct;49 (4) :104319.|Res Sq. 2024 Sep 22.|Research Square Preprint. 2021 Jul.|Research Square Preprint. 2022 Feb.|Research Square Preprint. 2022 May.|Research Square Preprint. 2023 Sep 8.|Research Square Preprint. 2024 Apr 9.|Respir Res. 2024 Jul 30;25 (1) :291.|SSRN. 2023 May 12.|SSRN. 2024 Nov 19.|SSRN. 6 Dec 2022.|Stem Cell Res Ther. 2025 May 1;16 (1) :222.|Structure. 2025 May 1;33 (5) :903-915.e5.|Transl Res. 2023 May:255:1-13.|Vet Microbiol. 2025 Aug:307:110628.|Vet Sci. 2024 Dec 12;11 (12) :643.
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
