GIV3727
GIV3727 is a bitter taste receptor hTAS2R antagonist, which can inhibit the activation of hTAS2R31 by saccharin and acesulfame potassium, and can effectively reduce the bitter quality of food, beverage and medicine[1].
Product Specifications
CAS Number
[957136-80-0]
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Taste Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/giv3727.html
Concentration
50.43 mM * 1 mL in Methanol
Purity
99.90
Solubility
10 mM in DMSO
Smiles
OC(CCCC1CCC(C1(C)C)C)=O
Molecular Formula
C12H22O2
Molecular Weight
198.30
Precautions
H315, H319, H335
References & Citations
[1]Jay P Slack, et al. Modulation of bitter taste perception by a small molecule hTAS2R antagonist. Curr Biol. 2010 Jun 22;20 (12) :1104-9.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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