9A1P9
9A1P9 is a multi-tail ionizable cationic phospholipid. 9A1P9 induces membrane destabilization. 9A1P9 can be used for mRNA delivery t[1].
Product Specifications
CAS Number
[2760467-57-8]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
CRISPR/Cas9; Liposome
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/9a1p9.html
Purity
99.40
Solubility
10 mM in DMSO
Smiles
O=P(OCCN(CCCCCCCC)CCCCCCCC)(OCCCCCCCCC)O
Molecular Formula
C27H58NO4P
Molecular Weight
491.73
Precautions
H302, H315, H319, H335
References & Citations
[1]Godbout K, et al. Delivery of RNAs to Specific Organs by Lipid Nanoparticles for Gene Therapy. Pharmaceutics. 2022 Oct 7;14 (10) :2129.|[2]Liu S, et al. Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR-Cas gene editing. Nat Mater. 2021 May;20 (5) :701-710.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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