MPEG-amine (MW 5000)

MPEG-amine (mPEG-NH2) (MW 5000) is a modifier that can replace the sulfonic acid portion of the dye molecule to increase the water solubility of long-wavelength voltage-sensitive dyes (VSD) or Pittsburgh (PGH) dyes. mPEG-amine can also form amide bonds with carboxyl groups on the surface of microspheres under the mediation of EDC and Sulfo-NHS to form a PEG coating on the surface of fluorescent microspheres for large-scale rotational cytoplasmic flow studies[1][2].

Product Specifications

CAS Number

[80506-64-5]

Product Name Alternative

MPEG-NH2 (MW 5000)

UNSPSC

12352200

Hazard Statement

H317, H319

Target

PROTAC Linkers

Type

Biochemical Assay Reagents

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mpeg-amine-mw-5000.html

Purity

99.70

Solubility

10 mM in DMSO

Smiles

COCCOCCN.[n]

Molecular Formula

(C2H4O) nC3H9NO

Molecular Weight

5000 (Average)

Precautions

H317, H319

References & Citations

[1]Patrick MJ, et al. Enhanced aqueous solubility of long wavelength voltage-sensitive dyes by covalent attachment of polyethylene glycol. Org Biomol Chem. 2007 Oct 21;5 (20) :3347-53.|[2]Suzuki K, et al. Spatial confinement of active microtubule networks induces large-scale rotational cytoplasmic flow. Proc Natl Acad Sci U S A. 2017 Mar 14;114 (11) :2922-2927.