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Succinic acid-Pomalidomide

Succinic acid-Pomalidomide is a E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACT (HY-168543) [1].

Product Specifications

CAS Number

[2417174-32-2]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/succinic-acid-pomalidomide.html

Purity

98.90

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CCC(O)=O

Molecular Formula

C17H15N3O7

Molecular Weight

373.32

Precautions

H302, H315, H319, H335

References & Citations

[1]Sflakidou E, et, al. Development of 2-Aminoadenine-Based Proteolysis-Targeting Chimeras (PROTACs) as Novel Potent Degraders of Monopolar Spindle 1 and Aurora Kinases. ACS Pharmacol. Transl. Sci. 2024.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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