Succinic acid-Pomalidomide
Succinic acid-Pomalidomide is a E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACT (HY-168543) [1].
Product Specifications
CAS Number
[2417174-32-2]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/succinic-acid-pomalidomide.html
Purity
98.90
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CCC(O)=O
Molecular Formula
C17H15N3O7
Molecular Weight
373.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Sflakidou E, et, al. Development of 2-Aminoadenine-Based Proteolysis-Targeting Chimeras (PROTACs) as Novel Potent Degraders of Monopolar Spindle 1 and Aurora Kinases. ACS Pharmacol. Transl. Sci. 2024.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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