M-PEG6-CH2CH2CHO
M-PEG6-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . m-PEG6-CH2CH2CHO is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product Specifications
CAS Number
[1058691-77-2]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m-peg6-ch2ch2cho.html
Purity
97.0
Solubility
10 mM in DMSO
Smiles
COCCOCCOCCOCCOCCOCCOCCC=O
Molecular Formula
C16H32O8
Molecular Weight
352.42
Precautions
H302, H315, H319, H335
References & Citations
[1]Erwin R. Boghaert, et al. Anti-egfr antibody drug conjugates. WO2017214282A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker; PEG Linkers
Available Sizes
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