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CGP 31358

CGP 31358 is an anticonvulsant agent that binds to a site on the NMDA receptor complex that is coupled to both the transmitter recognition site and to the channel domain. CGP 31358 inhibits the binding of L-Glutamate to the NMDA receptor complex with an IC50 of 53 μM[1].

Product Specifications

CAS Number

125652-47-3

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cgp-31358.html

Smiles

O=C(C1=NN(C2=CC=C(C(C)(C3=CC=C(Cl)C=C3)C)C=C2OC)C=N1)N

Molecular Formula

C19H19ClN4O2

Molecular Weight

370.83

References & Citations

[1]J Baud, et al. CGP 31358 binds to a site on the NMDA receptor that is coupled to both the transmitter recognition site and the channel domain. Neurosci Lett. 1989 Dec 15;107 (1-3) :184-8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

NMDA Receptor

Frequently Asked Questions

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