4-Amino-TEMPO

4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others[1][2].

Product Specifications

CAS Number

[14691-88-4]

Product Name Alternative

4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl

UNSPSC

12352200

Hazard Statement

H315, H319, H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/4-amino-tempo.html

Concentration

10mM

Purity

99.85

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

CC1(C)N([O])C(C)(C)CC(N)C1

Molecular Formula

C9H19N2O

Molecular Weight

171.26

Precautions

H315, H319, H335

References & Citations

[1]Żamojć K, Zdrowowicz M, Hać A, et al. Dihydroxy-substituted coumarins as fluorescent probes for nanomolar-level detection of the 4-amino-TEMPO spin label[J]. International journal of molecular sciences, 2019, 20 (15) : 3802.|[2]Gergely M, et al. 4‐Amino‐TEMPO as N‐Nucleophile in Palladium‐Catalyzed Aminocarbonylation. Journal of Heterocyclic Chemistry, 2017, 54 (1) : 634-640.