Cetirizine methyl ester

Cetirizine methyl ester is an impurity of Cetirizine (HY-17042) . Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist[1].

Product Specifications

CAS Number

[83881-46-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cetirizine-methyl-ester.html

Purity

96.05

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(COCCN1CCN(C(C2=CC=C(C=C2)Cl)C3=CC=CC=C3)CC1)OC

Molecular Formula

C22H27ClN2O3

Molecular Weight

402.91

Precautions

H302, H315, H319, H335

References & Citations

[1]Do JA, et al. Collision-induced dissociation pathways of H1-antihistamines by electrospray ionization quadrupole time-of-flight mass spectrometry. Arch Pharm Res. 2017 Jun;40 (6) :736-745.