Tadnersen (sodium)
Tadnersen sodium, an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion[1].
Product Specifications
Product Name Alternative
BIIB078 (sodium) ; IONIS-C9Rx (sodium)
UNSPSC
12352208
Target
Others; Ras
Type
Oligonucleotides
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tadnersen-sodium.html
Purity
99.30
Solubility
10 mM in H2O
Smiles
[Tadnersen(sodium)]
References & Citations
[1]Smeyers J, et al. C9ORF72: What It Is, What It Does, and Why It Matters. Front Cell Neurosci. 2021;15:661447. Published 2021 May 5.|[2]Aoki Y, et al. Emerging Oligonucleotide Therapeutics for Rare Neuromuscular Diseases [published online ahead of print, 2021 Jun 3]. J Neuromuscul Dis. 2021;10.3233/JND-200560.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
Phase 1
Available Sizes
Frequently Asked Questions
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