Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Mirogabalin

Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS.

Product Specifications

CAS Number

[1138245-13-2]

Product Name Alternative

DS5565

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Mirogabalin.html

Purity

99.22

Solubility

H2O : 7.71 mg/mL (ultrasonic)

Smiles

O=C(O)C[C@]1(CN)[C@]2([H])C=C(CC)C[C@]2([H])C1

Molecular Formula

C12H19NO2

Molecular Weight

209.29

Precautions

H315, H319, H335

References & Citations

[1]Vinik A, et al. Efficacy and safety of Mirogabalin (DS-5565) for the treatment of diabetic peripheral neuropathic pain: a randomized, double-blind, placebo- and active comparator-controlled, adaptive proof-of-concept phase 2 study. Diabetes Care. 2014 Dec|[2]Hutmacher MM, et al. Exposure-response modeling of average daily pain score, and dizziness and somnolence, forMirogabalin (DS-5565) in patients with diabetic peripheral neuropathic pain. J Clin Pharmacol. 2016 Jan;56 (1) :67-77.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-12650/Mirogabalin-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-12650/Mirogabalin-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

Launched

Citation 01

Brain Behav Immun. 2021 Jul:95:344-361.|Molecules. 2023 Nov 30;28 (23) :7862.|Pharmaceuticals (Basel) . 2022 Jan 13;15 (1) :88.|Pharmaceuticals (Basel) . 2023 Jul 19;16 (7) :1023.|Cell Commun Signal. 2024 Feb 1;22 (1) :92.

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

3-Acetyl-4-fluorobenzonitrile
PC908041-01 250 mg

3-Acetyl-4-fluorobenzonitrile

Ask
View Details
3-Acetyl-4-fluorobenzonitrile
PC908041-02 1 g

3-Acetyl-4-fluorobenzonitrile

Ask
View Details
3-Acetyl-4-fluorobenzonitrile
PC908041-03 5 g

3-Acetyl-4-fluorobenzonitrile

Ask
View Details
RFC4 (NM_002916) Human Over-expression Lysate
E45H06426-2 20 µg

RFC4 (NM_002916) Human Over-expression Lysate

Ask
View Details
RBM8A (RNA-binding Protein 8A, Binder of OVCA1-1, BOV-1, RNA-binding Motif Protein 8A, RNA-binding Protein Y14, Ribonucleoprotein RBM8A, RBM8, HSPC114, MDS014)
MBS6007295-01 0.05 mg

RBM8A (RNA-binding Protein 8A, Binder of OVCA1-1, BOV-1, RNA-binding Motif Protein 8A, RNA-binding Protein Y14, Ribonucleoprotein RBM8A, RBM8, HSPC114, MDS014)

Ask
View Details
RBM8A (RNA-binding Protein 8A, Binder of OVCA1-1, BOV-1, RNA-binding Motif Protein 8A, RNA-binding Protein Y14, Ribonucleoprotein RBM8A, RBM8, HSPC114, MDS014)
MBS6007295-02 5x 0.05 mg

RBM8A (RNA-binding Protein 8A, Binder of OVCA1-1, BOV-1, RNA-binding Motif Protein 8A, RNA-binding Protein Y14, Ribonucleoprotein RBM8A, RBM8, HSPC114, MDS014)

Ask
View Details