Posenacaftor (sodium)
Posenacaftor (PTI-801) sodium is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficking of CFTR protein. Posenacaftor sodium is used for the research of cystic fibrosis (CF) [1].
Product Specifications
CAS Number
2095064-06-3
Product Name Alternative
PTI-801 (sodium)
UNSPSC
12352005
Target
CFTR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/posenacaftor-sodium.html
Concentration
10mM
Purity
99.79
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(C2=C(C)C3=CC=CC=C3O2)=NC4=C(C)C=CC(O[C@@H](C5CCOCC5)C)=C14)O[Na]
Molecular Formula
C27H26NNaO5
Molecular Weight
467.49
References & Citations
[1]Benjamin Kopp, et al. Compositions et procédés pour améliorer la fonction cftr dans des cellules affectées par la fibrose kystique. Patent WO2019156946.|[2]Posenacaftor (PTI-801)
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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