Posenacaftor (sodium)

Posenacaftor (PTI-801) sodium is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficking of CFTR protein. Posenacaftor sodium is used for the research of cystic fibrosis (CF) [1].

Product Specifications

CAS Number

[2095064-06-3]

Product Name Alternative

PTI-801 (sodium)

UNSPSC

12352005

Target

CFTR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/posenacaftor-sodium.html

Concentration

10mM

Purity

99.79

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(C2=C(C)C3=CC=CC=C3O2)=NC4=C(C)C=CC(O[C@@H](C5CCOCC5)C)=C14)O[Na]

Molecular Formula

C27H26NNaO5

Molecular Weight

467.49

References & Citations

[1]Benjamin Kopp, et al. Compositions et procédés pour améliorer la fonction cftr dans des cellules affectées par la fibrose kystique. Patent WO2019156946.|[2]Posenacaftor (PTI-801)