FTO-IN-7
FTO-IN-7 (compound 17) is an inhibitor of FTO (fat mass and obesity-associated protein) with an IC50 of [1].
Product Specifications
CAS Number
2243736-37-8
UNSPSC
12352005
Target
Fat Mass and Obesity-associated Protein (FTO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fto-in-7.html
Concentration
10mM
Purity
99.22
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(C1=C(NC2=C(C=C(C3=C(C)NN=C3C)C=C2Cl)Cl)C=CC=C1)O
Molecular Formula
C18H15Cl2N3O2
Molecular Weight
376.24
References & Citations
[1]Yang, Caiguang, et al.Preparation of 2-substituted-benzene matrix compounds as FTO inhibitors.China, WO2018157843.2018-09-07.|[2]Liu Z, Duan Z, Zhang D, et al. Structure-Activity Relationships and Antileukemia Effects of the Tricyclic Benzoic Acid FTO Inhibitors. J Med Chem. 2022;65 (15) :10638-10654.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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