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FTO-IN-7

FTO-IN-7 (compound 17) is an inhibitor of FTO (fat mass and obesity-associated protein) with an IC50 of [1].

Product Specifications

CAS Number

2243736-37-8

UNSPSC

12352005

Target

Fat Mass and Obesity-associated Protein (FTO)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fto-in-7.html

Concentration

10mM

Purity

99.22

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C(C1=C(NC2=C(C=C(C3=C(C)NN=C3C)C=C2Cl)Cl)C=CC=C1)O

Molecular Formula

C18H15Cl2N3O2

Molecular Weight

376.24

References & Citations

[1]Yang, Caiguang, et al.Preparation of 2-substituted-benzene matrix compounds as FTO inhibitors.China, WO2018157843.2018-09-07.|[2]Liu Z, Duan Z, Zhang D, et al. Structure-Activity Relationships and Antileukemia Effects of the Tricyclic Benzoic Acid FTO Inhibitors. J Med Chem. 2022;65 (15) :10638-10654.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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