N-Boc-dolaproine-amide-Me-Phe
N-Boc-dolaproine-amide-Me-Phe is the amino acid residue of the pentapeptide Dolastatin 10. Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity[1].
Product Specifications
CAS Number
3026596-72-2
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Microtubule/Tubulin; Mitosis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-boc-dolaproine-amide-me-phe.html
Concentration
10mM
Purity
98.46
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@@H](C)CC2=CC=CC=C2)=O)OC)OC(C)(C)C
Molecular Formula
C23H36N2O4
Molecular Weight
404.54
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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