COX-2-IN-44
Product Specifications
UNSPSC Description
COX-2-IN-44 is a potent and orally active COX-2 inhibitor with IC50 values of 0.18,1.14 µM for COX-2, COX-1, respectively. COX-2-IN-44 shows anti-inflammatory activity[1].
Target Antigen
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cox-2-in-44.html
Smiles
CC(C=C1)=CC=C1NC(C(CC2=CC=C(Cl)C=C2)=C3)=NN=C3/C=C/C4=CC=C(OC)C=C4
Molecular Weight
441.95
References & Citations
[1]Ewieda SY, et al. Synthesis, COX-2 inhibition, anti-inflammatory activity, molecular docking, and histopathological studies of new pyridazine derivatives. Bioorg Chem. 2024 Sep;150:107623.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161862/COX-2-IN-44-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161862/
Clinical Information
No Development Reported
Curated Selection
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