What is the catalog number for AmmTX3 (TFA)?

The catalog number for AmmTX3 (TFA) is HY-P1426A.

What sizes are available for AmmTX3 (TFA)?

AmmTX3 (TFA) is available in the following size(s): 1 Each.

Is AmmTX3 (TFA) in stock?

AmmTX3 (TFA) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AmmTX3 (TFA)?

AmmTX3 (TFA) is manufactured by QuantiMol.

What is the estimated delivery time for AmmTX3 (TFA)?

Estimated delivery time for AmmTX3 (TFA) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for AmmTX3 (TFA)?

The safety data sheet for AmmTX3 (TFA) is available here: http://file.medchemexpress.com/batch_PDF/HY-P1426A/.

AmmTX3 (TFA)

AmmTX3 TFA is a peptide toxin that can be isolated from the venom of the scorpion Androctonus mauretanicus. AmmTX3 TFA is specific blocker of Kv4 channel. AmmTX3 TFA inhibits the A-type K+ current (Ki: 131 nM) [1][2].

Product Specifications

UNSPSC

12352209

Target

Potassium Channel

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ammtx3-tfa.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H](NC([C@@H](N1)CCC1=O)=O)[C@H](CC)C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H]2CCCCN)=O)=O)C)=O)C)=O)C(C)C)=O)=O)[C@H](CC)C)=O)C(C)C)=O)CCCCN)=O)CCCNC(N)=N)=O)CSSC[C@H](NC3=O)C(N[C@H](C(N4[C@H](C(O)=O)CCC4)=O)CC5=CC=C(O)C=C5)=O)=O)C(C)C)=O)CO)=O)C)=O)CSSC[C@H](NC6=O)C(N[C@H]3C(C)C)=O)=O)CO)=O)=O)=O)CCC(N)=O)=O)CSSC[C@H](NC2=O)C(N[C@H](C(N[C@H](C(NCC(N[C@H]6CCCNC(N)=N)=O)=O)CC(N)=O)=O)[C@H](CC)C)=O)=O)CCCCN)=O)CCCCN)=O)CC(N)=O)=O)[C@@H](C)O)=O)CCC(O)=O.O=C(O)C(F)(F)F.[x]

Molecular Formula

C158H262N50O48S6.xC2HF3O2

Molecular Weight

3822.47 (free acid)

References & Citations

[1]Vacher H, et al. Expanding the scorpion toxin alpha-KTX 15 family with AmmTX3 from Androctonus mauretanicus. Eur J Biochem. 2002 Dec;269 (24) :6037-41. https://|[2]Maffie JK, et al. Dipeptidyl-peptidase-like-proteins confer high sensitivity to the scorpion toxin AmmTX3 to Kv4-mediated A-type K+ channels. J Physiol. 2013 May 15;591 (10) :2419-27.