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Docetaxal

Product Specifications

UNSPSC Description

Docetaxal (10-Acetyl docetaxel) is an analog of Docetaxel (HY-B0011), with anticancer activity. Docetaxel is a microtubule disassembly inhibitor, with antimitotic activity[1][2].

Target Antigen

ADC Cytotoxin

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/docetaxal.html

Purity

99.54

Solubility

DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

CC(O[C@@]1([C@](C2)([H])OC1)[C@@]([C@](C([C@@H]3OC(C)=O)=O)([C@H]2O)C)([H])[C@@H]([C@@](C(C)(C3=C4C)C)(C[C@@H]4OC([C@H](O)[C@H](C5=CC=CC=C5)NC(OC(C)(C)C)=O)=O)O)OC(C6=CC=CC=C6)=O)=O

Molecular Weight

849.92

References & Citations

[1]Gueritte-Voegelein, et al. Relationships between the structure of taxol analogs and their antimitotic activity. Journal of Medicinal Chemistry, 1991. 34(3), 992–998.|[2]Yao, Peng, et al. Preparation of crystal form of dihydrate and DMSO solvate of anticancer compound CX1409. CN107793382A.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-B0018/Docetaxal-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-B0018/Docetaxal-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

125354-16-7

Available Sizes

Curated Selection

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