AITRL/TNFSF18, Human (HEK293, Fc)
Selected Variant
HY-P76110
Size: 1 Each
AITRL, a type II transmembrane protein, is a ligand for glucocorticoid-induced TNFR-related protein (GITR) . When AITRL binds to GITR, GITR can produce costimulatory signals that regulate T-cell proliferation and effector functions. GITR/AITRL interaction plays a role in the pathogenesis of tumor, inflammation, as well as autoimmune diseases[1]. Besides, AITRL plays a role in endothelial cells (EC) -activation and increases STAT-1 phosphorylation and the expression of adhesion molecules (VCAM-1, ICAM-1) [2]. AITRL/TNFSF18 Protein, Human (HEK293, Fc) is a recombinant human AITRL (Q72-S199) with C-terminal mFc tag, which is expressed in HEK293.
Product Specifications
Product Name Alternative
AITRL/TNFSF18 Protein, Human (HEK293, Fc), Human, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/aitrl-tnfsf18-protein-human-hek293-fc.html
Molecular Formula
8995 (Gene_ID) Q9UNG2/NP_005083.3 (Q50-S177) (Accession)
Molecular Weight
Approximately 45.5 kDa, based on SDS-PAGE under reducing conditions.
References & Citations
Shipping Conditions
Dry ice.
Scientific Category
Recombinant Proteins
Price
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
MUC2 (Mucin 2) (MLP/2970R), CF594 conjugate, 0.1mg/mL
Anti-FOXA1/Hnf 3 Alpha Rabbit Monoclonal Antibody
CD3e (T-Cell Marker) (C3e/2479), CF568 conjugate, 0.1mg/mL
Anti-Aquaporin 2/AQP2 Antibody Picoband® (APC Conjugate)
