(+) -Biotin-ONP
(+) -Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[33755-53-2]
Product Name Alternative
(+) -Biotin 4-nitrophenyl ester
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/plus-biotin-onp.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C(OC1=CC=C([N+]([O-])=O)C=C1)CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O
Molecular Formula
C16H19N3O5S
Molecular Weight
365.40
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl-Chain Linkers
Available Sizes
Curated Selection
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