Tos-PEG3
Tos-PEG3 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports[1].
Product Specifications
CAS Number
[77544-68-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tos-peg3.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic;warming)|Ethanol : 100 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic)
Smiles
OCCOCCOCCOS(C1=CC=C(C)C=C1)(=O)=O
Molecular Formula
C13H20O6S
Molecular Weight
304.36
Precautions
H302, H315, H319, H335
References & Citations
[1]Noël M, et al. Solid Supports for the Synthesis of 3'-Aminooxy Deoxy- or Ribo-oligonucleotides and Their 3'-Conjugation by Oxime Ligation.J Org Chem. 2019 Nov 15;84 (22) :14854-14860.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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