Transthyretin/TTR, Human (127a.a, HEK293, His)

Transthyretin (TTR) belongs to the serum transporter family and is a plasma transporter of T4 and retinol. Transthyretin inhibits Aβ1-42 fibrillization and is a potential target for amyloidosis and Alzheimer's disease. Transthyretin mutations (such as V30M) can destabilize the tetramer and promote the formation of amyloid fibrils in monomers, causing hereditary amyloidosis transthyretin (ATTRv) . Transthyretin/TTR Protein, Human (127a.a, HEK293, His) is a recombinant transthyretin/TTR protein expressed in HEK293 with a C-6*His tag.