SL 0101-1
SL 0101-1 (SL0101), a kaempferol glycoside, isolated from the tropical plant F. refracta, is a cell-permeable, selective, reversible, ATP-competitive p90 Ribosomal S6 Kinase (RSK) inhibitor, with an IC50 of 89 nM[1]. SL 0101-1 (SL0101) is a selective RSK1/2 inhibitor, with a Ki of 1 μM[2].
Product Specifications
CAS Number
77307-50-7
Product Name Alternative
SL0101
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ribosomal S6 Kinase (RSK)
Type
Natural Products
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SL_0101-1.html
Purity
98.0
Solubility
DMSO : 10 mg/mL (ultrasonic; warming)
Smiles
OC1=CC(O)=C(C(C(O[C@@H]2O[C@@H](C)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]2O)=C(C3=CC=C(O)C=C3)O4)=O)C4=C1
Molecular Formula
C25H24O12
Molecular Weight
516.45
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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