TNIK-IN-7

TNIK-IN-7 (Compound 8) is an inhibitor of Traf2 and Nck-interacting kinase (TNIK), with IC50 of 11 nM, that has antitumor activity[1].

Product Specifications

CAS Number

[1417795-24-4]

UNSPSC

12352005

Target

Ser/Thr Protease

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tnik-in-7.html

Purity

99.90

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

N#CC1=CC=C(OC)C(C2=CC(NC3=CC=C(N4CCOCC4)C=C3)=NC=C2)=C1

Molecular Formula

C23H22N4O2

Molecular Weight

386.45

References & Citations

[1]Koc-Kan Ho, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23 (2) :569-73.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP3-20776JF669 0.1 mL

Mouse Monoclonal Calbindin D-28K Antibody (rCALB1/8499) [Janelia Fluor 669]

Ask

View Details

MBS9202447-01 0.08 mL

CCDC12 Antibody (N-term)

Ask

View Details

MBS9202447-02 0.4 mL

CCDC12 Antibody (N-term)

Ask

View Details

MBS9202447-03 5x 0.4 mL

CCDC12 Antibody (N-term)

Ask

View Details

MAB1116-SP 25 µg

Rat CXCL7/Thymus Chemokine-1 MAb (Clone 186701)

Ask

View Details

EKU02853 96 Tests

Human Calcitonin (CT) ELISA Kit

Ask

View Details