CCR1 antagonist 9
CCR1 antagonist 9 is a potent and selective CCR1 antagonist with an IC50 of 6.8 nM in calcium flux assay[1].
Product Specifications
CAS Number
[1220026-26-5]
UNSPSC
12352005
Target
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ccr1-antagonist-9.html
Concentration
10mM
Purity
99.65
Solubility
DMSO : 83.33 mg/mL (ultrasonic)
Smiles
O=C(C1=CN=CC2=C1C=NN2C3=CC=C(F)C=C3)NCC4=CC(S(=O)(C)=O)=NC=C4
Molecular Formula
C20H16FN5O3S
Molecular Weight
425.44
References & Citations
[1]Harcken C, et al. Identification of novel azaindazole CCR1 antagonist clinical candidates. Bioorg Med Chem Lett. 2019 Feb 1;29 (3) :441-448.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CCR1
Available Sizes
Curated Selection
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