5'-O-DMT-ibu-rG
5'-O-DMT-ibu-rG is a useful model for a new class of DNA binding molecules for the development of potent and selective anti-cancer agents[1].
Product Specifications
CAS Number
[81246-83-5]
Product Name Alternative
5'-O-DMT-N2-isobutyrylguanosine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others; Cancer
Assay Protocol
https://www.medchemexpress.com/5-o-dmt-ibu-rg.html
Purity
95.39
Solubility
DMSO : 175 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=C(NC(C(C)C)=O)NC3=O)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6
Molecular Formula
C35H37N5O8
Molecular Weight
655.70
Precautions
H302, H315, H319, H335
References & Citations
[1]Pradeepkumar Patel, et al. Synthesis, DNA binding and anti-leukemic activity of an aminoacyl nucleolipid. Bioorg Med Chem Lett. 2013 Sep 15;23 (18) :5086-90.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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