Diethyl succinate-13C4

Diethyl succinate-13C4 is the 13C labeled Diethyl succinate[1]. Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes, incorporates into cells in tissue culture and is metabolized by the TCA cycle. Diethyl succinate is known to be non-toxic and used in fragrances and flavoring[2].

Product Specifications

CAS Number

[1628796-56-4]

Product Name Alternative

1,4-Diethyl butanedioate-1,2,3,4-13C4

UNSPSC

12352211

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/diethyl-succinate-13c4.html

Purity

99.9

Solubility

10 mM in DMSO

Smiles

CCO[13C]([13CH2][13CH2][13C](OCC)=O)=O

Molecular Formula

C4 13C4H14O4

Molecular Weight

178.16

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Zacharias NM, et al. Real-time molecular imaging of tricarboxylic acid cycle metabolism in vivo by hyperpolarized 1- (13) C diethyl succinate. J Am Chem Soc. 2012 Jan 18;134 (2) :934-43.