Fructosyl-lysine

Fructosyl-lysine (Fructoselysine) is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction. Fructosyl-lysine is the precursor to glucosepane, a lysine-arginine protein cross-link that can be an indicator in diabetes detection[1].

Product Specifications

CAS Number

[21291-40-7]

Product Name Alternative

Fructoselysine

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/fructosyl-lysine.html

Purity

99.86

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

N[C@H](C(O)=O)CCCCNCC([C@@H](O)[C@H](O)[C@H](O)CO)=O

Molecular Formula

C12H24N2O7

Molecular Weight

308.33

Precautions

H315, H319, H335

References & Citations

[1]Rabbani N, et al. Hidden complexities in the measurement of fructosyl-lysine and advanced glycation end products for risk prediction of vascular complications of diabetes. Diabetes. 2015 Jan;64 (1) :9-11.|[2]Karachalias N, et al. Accumulation of fructosyl-lysine and advanced glycation end products in the kidney, retina and peripheral nerve of streptozotocin-induced diabetic rats. Biochem Soc Trans. 2003 Dec;31 (Pt 6) :1423-5.