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N6-Methyl-dA phosphoramidite

N6-Methyl-dA phosphoramidite can be used in the synthesis of oligodeoxyribonucleotides[1].

Product Specifications

CAS Number

[105931-58-6]

UNSPSC

12352005

Hazard Statement

H315-H317-H319-H335-H360

Target

DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/n6-methyl-da-phosphoramidite.html

Concentration

10mM

Purity

99.83

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

COC1=CC=C(C(C2=CC=C(OC)C=C2)(OC[C@@H]3[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)C[C@H](N4C(N=CN=C5NC)=C5N=C4)O3)C6=CC=CC=C6)C=C1

Molecular Formula

C41H50N7O6P

Molecular Weight

767.85

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Li D, et, al. Exocyclic carbons adjacent to the N6 of adenine are targets for oxidation by the Escherichia coli adaptive response protein AlkB. J Am Chem Soc. 2012 May 30;134 (21) :8896-901.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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