N6-Methyl-dA phosphoramidite
N6-Methyl-dA phosphoramidite can be used in the synthesis of oligodeoxyribonucleotides[1].
Product Specifications
CAS Number
105931-58-6
UNSPSC
12352005
Hazard Statement
H315-H317-H319-H335-H360
Target
DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/n6-methyl-da-phosphoramidite.html
Concentration
10mM
Purity
99.83
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
COC1=CC=C(C(C2=CC=C(OC)C=C2)(OC[C@@H]3[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)C[C@H](N4C(N=CN=C5NC)=C5N=C4)O3)C6=CC=CC=C6)C=C1
Molecular Formula
C41H50N7O6P
Molecular Weight
767.85
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Li D, et, al. Exocyclic carbons adjacent to the N6 of adenine are targets for oxidation by the Escherichia coli adaptive response protein AlkB. J Am Chem Soc. 2012 May 30;134 (21) :8896-901.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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