N, N'-Dinitrosopiperazine

N, N'-Dinitrosopiperazine (1,4-Dinitrosopiperazine; DNP) is a carcinogen with specificity for nasopharyngeal epithelium and facilitates NPC metastasis. N, N'-Dinitrosopiperazine regulates multiple signaling pathways through protein phosphorylation, including LYRIC at serine 568[1].

Product Specifications

CAS Number

[140-79-4]

Product Name Alternative

1,4-Dinitrosopiperazine; DNP

UNSPSC

12352005

Hazard Statement

H301, H315, H319, H335, H350

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-n-dinitrosopiperazine.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=NN1CCN(N=O)CC1

Molecular Formula

C4H8N4O2

Molecular Weight

144.13

Precautions

H301, H315, H319, H335, H350

References & Citations

[1]Damao Huang, et al. Identification of Novel Signaling Components in N, N'-dinitrosopiperazine-mediated Metastasis of Nasopharyngeal Carcinoma by Quantitative Phosphoproteomics. BMC Cancer. 2014 Apr 5;14:243.