KY-02327 (acetate)
Product Specifications
UNSPSC Description
KY-02327 acetate, a metabolically stabilized KY-02061 analog, is a potent Dishevelled (Dvl)-CXXC5 interaction inhibitor. KY-02327 acetate shows an activating effect on the Wnt/β-catenin pathway, resulting in promotion of osteoblast differentiation[1].
Target Antigen
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ky-02327-acetate.html
Purity
99.35
Solubility
DMSO : 140 mg/mL (ultrasonic;warming;heat to 80°C)|H2O : ≥ 160 mg/mL
Smiles
O=C(C(N1CC(NCCN2CCCCC2)=O)=CC3=C1C=CC(O)=C3)OCC.CC(O)=O
Molecular Weight
433.50
References & Citations
[1]Kim HY, et al. Small molecule inhibitors of the Dishevelled-CXXC5 interaction are new drug candidates for bone anabolic osteoporosis therapy. EMBO Mol Med. 2016;8(4):375-387.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-124156A/KY-02327-acetate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-124156A/KY-02327-acetate-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2989396-34-9
Available Sizes
Curated Selection
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