KY-02327 (acetate)
KY-02327 acetate, a metabolically stabilized KY-02061 analog, is a potent Dishevelled (Dvl) -CXXC5 interaction inhibitor. KY-02327 acetate shows an activating effect on the Wnt/β-catenin pathway, resulting in promotion of osteoblast differentiation[1].
Product Specifications
CAS Number
[2989396-34-9]
UNSPSC
12352005
Target
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ky-02327-acetate.html
Purity
99.24
Solubility
DMSO : 140 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : ≥ 160 mg/mL
Smiles
O=C(C(N1CC(NCCN2CCCCC2)=O)=CC3=C1C=CC(O)=C3)OCC.CC(O)=O
Molecular Formula
C22H31N3O6
Molecular Weight
433.50
References & Citations
[1]Kim HY, et al. Small molecule inhibitors of the Dishevelled-CXXC5 interaction are new drug candidates for bone anabolic osteoporosis therapy. EMBO Mol Med. 2016;8 (4) :375-387.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV713488 1.0 µg DNA
PITRM1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)
Sign In for Pricing
View Details 
F6720 96 Tests
Pancreas Transcription Factor 1 subunit α (PTF1A) Human ELISA Kit
Sign In for Pricing
View Details