BPIPP

BPIPP is a guanylyl cyclase type C (GC-C) and adenylyl cyclase inhibitor that can suppress cyclic nucleotide synthesis. BPIPP inhibits chloride-ion transport stimulated by activation of guanylyl or adenylyl cyclases, and has the potential for diarrhea research[1].

Product Specifications

CAS Number

[325746-94-9]

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Adenylate Cyclase; Guanylate Cyclase

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/bpipp.html

Purity

98.3

Smiles

O=C1C2=C(C3=CC=CC=C13)NC(N(C(N(C)C4=O)=O)C)=C4C2C5=CC(Br)=CC=C5

Molecular Formula

C22H16BrN3O3

Molecular Weight

450.28

Precautions

H315, H319, H320

References & Citations

[1]Alexander Y Kots, et al. Pyridopyrimidine derivatives as inhibitors of cyclic nucleotide synthesis: Application for treatment of diarrhea. Proc Natl Acad Sci U S A. 2008 Jun 17;105 (24) :8440-5.