EGFR ligand-11
Product Specifications
UNSPSC Description
EGFR ligand-11 is a target protein ligand for EGFR and can be used to synthesize PROTAC MS154 (HY-141640)[1].
Target Antigen
EGFR; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
JAK/STAT Signaling;PROTAC;Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-ligand-11.html
Smiles
FC(C(Cl)=C1)=CC=C1NC2=C(C(C=C3OC)=NC=N2)C=C3OCCCN4CCN(CCC(O)=O)CC4
Molecular Weight
517.98
References & Citations
[1]Meng Cheng, et al. Discovery of Potent and Selective Epidermal Growth Factor Receptor (EGFR) Bifunctional Small-molecule Degraders. J Med Chem. 2020 Feb 13;63(3):1216-1232.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168305/EGFR-ligand-11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168305/
Clinical Information
No Development Reported
CAS Number
2550394-08-4
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