STS-E412

STS-E412 is a selective activator of tissue-protective EPO receptor (including EPOR and CD131) . STS-E412 can be used for research of neurodegenerative diseases and organ protection[1].

Product Specifications

CAS Number

1609980-39-3

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

JAK

Type

Reference compound

Related Pathways

Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sts-e412.html

Concentration

10mM

Purity

99.72

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

CC1=CC(C)=NC2=NC(OCCOC3=CC=C(Cl)C=C3)=NN12

Molecular Formula

C15H15ClN4O2

Molecular Weight

318.76

Precautions

H302, H315, H319

References & Citations

[1]Miller JL, et al. Discovery and Characterization of Nonpeptidyl Agonists of the Tissue-Protective Erythropoietin Receptor. Mol Pharmacol. 2015 Aug;88 (2) :357-67.