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Harmalol (hydrochloride)

Harmalol hydrochloride, a beta carboline alkaloid, presents in several medicinal plants such as Peganum harmala. Harmalol hydrochloride, main metabolite of Harmaline, significantly inhibits the dioxin-mediated induction of CYP1A1 at the transcriptional and posttranslational levels. Harmalol hydrochloride possesses antioxidant and hydroxyl radical-scavenging properties[1].

Product Specifications

CAS Number

6028-07-5

UNSPSC

12352005

Target

Cytochrome P450

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/harmalol-hydrochloride.html

Purity

99.91

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=NCCC2=C1NC3=C2C=CC(O)=C3.[H]Cl

Molecular Formula

C12H13ClN2O

Molecular Weight

236.70

References & Citations

[1]El Gendy MA, et al. Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms. Food Chem Toxicol. 2012;50 (2) :353-362.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

CYP1

Available Sizes

Frequently Asked Questions

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